publications
2011
Sander LE, Davis MJ, Boekschoten MV, Amsen D, Dascher CC, Ryffel B,
Swanson JA, Müller M, Blander JM.
Detection of prokaryotic mRNA signifies microbial viability and
promotes immunity.
Nature. 2011
May 22;474(7351):385-9.
de Wit NJ, Boekschoten MV, Bachmair EM, Hooiveld GJ, de Groot PJ,
Rubio-Aliaga I, Daniel H, Müller M.
Dose-dependent effects of dietary fat on development of obesity in
relation to intestinal differential gene expression in C57BL/6J
mice.
PLoS One. 2011
Apr 25;6(4):e19145.
Mattijssen F, Kersten S.
Saturated Fatty Acids and snoRNAs: Partners in Crime.
Cell Metab.
2011 Jul 6;14(1):1-2.
Zhu P, Tan MJ, Huang RL, Tan CK, Chong HC, Pal M, Lam CR, Boukamp P,
Pan JY,
Tan SH, Kersten S, Li HY, Ding JL, Tan NS.
Angiopoietin-like 4 protein elevates the prosurvival intracellular
O2(-):H2O2 ratio and confers anoikis resistance to tumors.
Cancer Cell.
2011 Mar 8;19(3):401-15.
Stienstra R, Kersten S.
Fight fat with
DGAT. J Lipid Res. 2011 Apr;52(4):591-2.
Clement LC, Avila-Casado C, Macé C, Soria E, Bakker WW, Kersten S,
Chugh SS.
Podocyte-secreted angiopoietin-like-4 mediates proteinuria in
glucocorticoid-sensitive nephrotic syndrome.
Nat Med. 2011
Jan;17(1):117-22.
Rubio-Aliaga I, Roos B, Sailer M, McLoughlin GA, Boekschoten MV, van
Erk M, Bachmair EM, van Schothorst EM, Keijer J, Coort SL, Evelo
C, Gibney MJ, Daniel H, Müller M, Kleemann R, Brennan L.
Alterations in hepatic one-carbon metabolism and related pathways
following a high-fat dietary intervention.
Physiol
Genomics 2011 Apr 27;43(8):408-16.
de Wit NJ, Bosch-Vermeulen H, Oosterink E, Müller M, van der Meer R.
Supplementary dietary calcium stimulates faecal fat and bile acid
excretion, but does not protect against obesity and insulin
resistance in C57BL/6J mice.
Br J Nutr.
2011 Apr;105(7):1005-11.
Beraza N, Ofner-Ziegenfuss L, Ehedego H, Boekschoten M, Bischoff SC,
Müller M, Trauner M, Trautwein C.
Nor-ursodeoxycholic acid reverses hepatocyte-specific nemo-dependent
steatohepatitis.
Gut. 2011
60:387-96.
2010
1. Vaes BL, Lute C, van der Woning SP, Piek E, Vermeer J, Blom HJ,
Mathers JC, Müller M, de Groot LC, Steegenga WT Inhibition of
methylation decreases osteoblast
differentiation via a non-DNA methylation dependent mechanism.
Bone. 2010;46:514-23
2. Stienstra R, Saudale F, Duval C, Keshtkar S, Groener JEM, van
Rooijen N, Staels B, Kersten S, Müller M
Kupffer cells promote hepatic steatosis via IL-1β
dependent suppression of PPARalpha activity. Hepatology.
2010;51:511-22
3. Herrema H, Meissner M, van Dijk TH, Brufau G, Boverhof R,
Oosterveer MH, Reijngoud DJ, Müller M,
Stellaard F, Groen AK, Kuipers F. Bile salt sequestration induces
hepatic de novo lipogenesis via FXR and LXR-controlled metbaolic
pathways in mice. Hepatology. 2010;51:806-16.
4. Lu Y, Feskens EJ, Boer JM, Müller M. The potential influence of
genetic variants in genes along bile acid and bile metabolic pathway
on blood cholesterol levels in the population. Atherosclerosis.
2010;210:14-27
5. Bouwens M, Grootte Bromhaar M, Jansen J, Müller M, Afman LA.
Postprandial dietary lipid-specific effects on human peripheral
blood mononuclear cell gene expression profiles. Am J Clin Nutr.
2010;91:208-17
6. van der Meer DL, Degenhardt T, Väisänen S, de Groot PJ,
Heinäniemi M,
de Vries SC, Müller M, Carlberg C, Kersten S. Profiling of promoter
occupancy by PPARa in human hepatoma cells via ChIP-chip analysis. Nucleic Acids Res.
2010;38:2839-50
7. Georgiadi A, Lichtenstein L, Degenhardt T, Boekschoten M, van
Bilsen M, Desvergne B, Müller M, Kersten S. Induction of Cardiac
Angptl4 by Dietary Fatty Acids Is Mediated by PPAR b/d and Protects
Against Fatty Acid-Induced Oxidative Stress. Circ Res.
2010;106:1712-21
8. Sanderson LM, Boekschoten MV, Desvergne B, Müller M, Kersten S.
Transcriptional profiling reveals divergent roles of PPARalpha and
PPARbeta/delta in regulation of gene expression in mouse liver.
Physiol Genomics. 2010;41:42-52
9. Lu Y, Feskens EJ, Dollé ME, Imholz S, Verschuren WM, Müller M,
Boer JM Dietary n-3 and n-6 polyunsaturated fatty acid intake
interacts with FADS1 genetic variation to affect total and HDL
cholesterol levels in the Doetinchem Cohort Study.
Am J Clin Nutr 2010;92:1–8
10. Sander LE, Sackett SD, Dierssen U, Beraza N, Linke RP, Müller M,
Blander JM, Tacke F, Trautwein C. Hepatic acute-phase proteins
control innate immune responses during infection by promoting
myeloid-derived suppressor cell function. J Exp Med.
2010;207:1453-64.
11. Caesar R, Manieri M, Kelder T, Boekschoten M, Evelo C, Müller M,
Kooistra T, Cinti S, Kleemann R, Drevon CA. A combined
transcriptomics and lipidomics analysis of subcutaneous, epididymal
and mesenteric adipose tissue reveals marked functional differences.
PLoS One. 2010;5:e11525.
12. Martins dos Santos V, Müller M, de Vos WM. Systems biology of
the gut:
the interplay of food, microbiota and host at the mucosal
interface. Curr Opin Biotechnol. 2010;21:539-50.
13. van Ommen B, Bouwman J, Dragsted LO, Drevon CA, Elliott R, de
Groot P, Kaput J, Mathers JC, Müller M, Pepping F, Saito J, Scalbert
A, Radonjic M, Rocca-Serra P, Travis A, Wopereis S, Evelo CT.
Challenges of molecular nutrition research 6: the nutritional
phenotype database to store, share and evaluate nutritional systems
biology studies. Genes Nutr. 2010;5:189-203.
14. Rakhshandehroo M, Knoch B, Müller M, Kersten S. Peroxisome
proliferator-activated receptor alpha target genes. PPAR Res. 2010;
pii:612089
15. Lu Y, Feskens EJ, Boer JM, Imholz S, Verschuren WM, Wijmenga C,
Vaarhorst A, Slagboom E, Müller M, Dollé ME. Exploring genetic
determinants of plasma total cholesterol levels and their predictive
value in a longitudinal study. Atherosclerosis. 2010
Nov;213(1):200-5.
16. Bettermann K, Vucur M, Haybaeck J, Koppe C, Janssen J, Heymann
F, Weber A, Weiskirchen R, Liedtke C, Gassler N, Müller M, de Vos R,
Wolf MJ, Boege Y, Seleznik GM, Zeller N, Erny D, Fuchs T, Zoller S,
Cairo S, Buendia MA, Prinz M, Akira S, Tacke F, Heikenwalder M,
Trautwein C, Luedde T. TAK1 suppresses a NEMO-dependent but
NF-kB-independent pathway to liver cancer. Cancer Cell 2010;17:481-496
17. Stienstra R, Joosten LA, Koenen T, van Tits B, van Diepen JA,
van den Berg SA, Rensen PC, Voshol PJ, Fantuzzi G, Hijmans A,
Kersten S, Müller M, van den Berg WB, van Rooijen N, Wabitsch M,
Kullberg BJ, van der Meer JW, Kanneganti T, Tack CJ, Netea MG. The
inflammasome-mediated caspase-1 activation controls adipocyte
differentiation and insulin sensitivity. Cell Metab.
2010;12:593-605.
18. Lichtenstein L, Mattijssen F, de Wit NJ, Georgiadi A, Hooiveld
GJ, van der Meer R, He Y, Qi L, Köster A, Tamsma JT, Tan NS, Müller
M, Kersten S. Angptl4 Protects against Severe Proinflammatory
Effects of Saturated Fat by Inhibiting Fatty Acid Uptake into
Mesenteric Lymph Node Macrophages. Cell Metab. 2010;12:580-92.
19. Duval C, Thissen U, Keshtkar S, Accart B, Stienstra R,
Boekschoten MV, Roskams T, Kersten S, Müller M. Adipose tissue
dysfunction signals progression of hepatic steatosis towards
nonalcoholic steatohepatitis in C57BL/6 mice. Diabetes.
2010;59:3181-91.
20. Van Baarlen P, Troost F, van der Meer C, Hooiveld GJEJ,
Boekschoten MV, Brummer RJ, Kleerebezem M. Human mucosal in vivo
transcriptome responses to three lactobacilli indicate how
probiotics may modulate human cellular pathways. Proc Natl Acad Sci
USA, 2010, epub
21. De Wilde J, Smit E, Mohren R, Boekschoten MV, De Groot P, Van
den Berg SA, Bijland S, Voshol PJ, Willems-Van Dijk K, De Wit NW,
Bunschoten A, Schaart G, Hulshof MF, Mariman EC. An 8-week high-fat
diet induces obesity and insulin resistance with small changes in
the muscle transcriptome of C57BL/6J mice.
J Nutrigenet
Nutrigenomics, 2010, 2(6):280-291
22. Hessvik NP, Bakke SS, Fredriksson K, Boekschoten MV, Fjørkenstad
A, Koster G, Hesselink MK, Kersten S, Kase ET, Rustan AC, Thoresen
GH. Metabolic switching of human myotubes is improved by n-3 fatty
acids. J Lipid Res, 2010, 51:2090-2104
23. De Wilde J, Hulshof MFM, Boekschoten MV, De Groot PJ, Smit E,
Mariman ECM.The embryonic genes Dkk3, Hoxd8, Hoxd9 and Tbx1 identify
muscle types in a diet-independent and fiber-type unrelated way. BMC
Genomics, 2010, 11:176
24. Van Cruchten STJ, de Waart R, Kunne C, Hooiveld GJEJ,
Boekschoten MV, Katan MB, Oude Elferink RPJ, Witkamp RF. Absorption,
distribution and biliary excretion of cafestol, a potent
cholesterol-elevating compound in unfiltered coffees in mice. Drug
Metab Dispos, 2010, 38:635-640
25. Hessvik NP, Boekschoten MV, Baltzersen MA, Kersten S, Xu X,
Andersén H, Rustan AC, Thoresen GH. Liver X receptor β (LXRβ) is the
dominant LXR subtype in skeletal muscle regulating lipogenesis and
cholesterol efflux. Am J Physiol Endocrinol Metab, 2010, 298:E602-13
26. Van Cruchten STJ, de Haan LHJ, Mulder PPJ, Cunne C, Boekschoten
MV, Katan MB, Aarts JMMJG, Witkamp RF. The role of epoxidation and
activation of the electrophile-responsive element (EpRE) in the
potential beneficial and harmful effects of the coffee component(s)
cafestol and kahweol. J Nutr Biochem, 2010, 21:757-763
27. Goh YY, Pal M, Chong HC, Zhu P, Tan MJ, Punugu L, Tan CK, Huang
R,
Tang MB, Ding JL, Kersten S, Tan NS. Angiopoietin-like 4
interacts with matrix proteins to modulate wound healing. J. Biol.
Chem. 2010, 285:32999-3009
28. Goh YY, Pal M, Chong HC, Zhu P, Tan, MJ, Punuga L, Yau YH, Tan
CK, Huang R, Tan SM, Tang MB, Ding JL, Kersten S, Tan NS.
Angiopoietin-like 4 interacts with integrins β1 and β5 to modulate
keratinocyte migration. Am. J. Pathol. 177:2791-803. (2010)
29. De Vogel-van den Bosch J, Hoeks J, Timmers S, Houten SM, van
Dijk PJ, Boon W, Van Beurden D, Schaart G, Kersten S, Voshol PJ,
Wanders RJA, Hesselink MK, Schrauwen P. The effects of long- or
medium-chain fat diets on glucose toleranceand myocellular content
of lipid intermediates in rats. Obesity. (2010)
30. Lichtenstein L, Kersten S. Modulation of plasma TG lipolysis by
Angiopoietin-like proteins and GPIHBP1. Biochim. Biophys. Acta.
1801:415-20 (2010)
31. Vallanat B, Anderson SP, Brown-Borg HM, Ren H, Kersten S,
Jonnalagadda S, Srinivasan S, Corton JC. Analysis of the heat shock
response in mouse liver reveals dependence on the Nuclear Receptor
Peroxisome Proliferator-Activated Receptor alpha. BMC Genomics.
11:16 (2010)
32. N.J.W. de Wit, H. Bosch-Vermeulen, E. Oosterink, M. Muller, R
van der Meer. Supplementary dietary calcium stimulates faecal fat
and bile acid excretion,
but does not protect against obesity and
insulin resistance in C57BL/6J mice. British Journal of Nutrition
(2010), page 1 of 7
33. SJ. van Dijk, EJM. Feskens, AG Heidema, MB Bos, O. van de Rest,
J.M. Geleijnse, L.C de Groot, M Müller, LA. Afman. Plasma Protein
Profiling Reveals Protein Clusters Related to BMI and Insulin Levels
in Middle-Aged Overweight Subjects. PLOS One 2010 e14422